National Sun Yat-sen University

Introduction

Wei-Lung Tseng’s research encompasses a wide range of areas related to the synthesis and application of nanoparticles in biosensing, capillary electrophoresis, catalysis, and extraction. Moreover, he designed a series of oligonucleotides for use as molecular beacons and optical sensors based on non-Watson-Crick base pairing. The work spans analytical chemistry, materials chemistry, and, more recently, bioanalytical and environmental chemistry. He has demonstrated the practical applicability of these sensor types for detecting heavy metal ions, aminothiols, hydrogen peroxide, cyanide, enzyme activity, single nucleotide polymorphisms, and the anticancer drug coralyne. Dr. Tseng has authored and co-authored more than 200 peer-reviewed scientific journal articles, with more than 9500 citations (Google Scholar data). The h-index of 56, after 11 years of scientific activity, clearly indicates his consistent publication record (data from Google Scholar). Tseng’s recent publications, including Anal. Chem. 2010, Vol. 82, pp. 6830, Anal. Chem. 2010, Vol. 82, pp. 9194, Small 2012, Vol. 8, pp.1912, identified as a “Highly cited paper”. Tseng’s recent works have been highlighted in Nanoscale (The Inside of the Back Cover, Nanoscale, 2014, Vol. 6, pp. 1347; The Inside of the Back Cover, 2014, Vol. 6, pp. 9618), Chem. Commun. (the inside of the back cover, 2013, Vol. 49, pp. 4607), Phys. Chem. Chem. Phys. (the inside of Front Cover, 2015, Vol. 17, pp. 15124), Particle & Particle Systems Characterization (Front Cover, 2016, Vol. 33, pp.132), Adv. Funct. Mater. (Frontispiece, 2017, Vol. 27, pp. 1702452), and Nanoscale Adv. (Inside Cover, 2021. Vol. 3, pp 661-667). 

Please see my recent publication: https://scholar.google.com/citations?user=v2XEd2MAAAAJ&hl=zh-TW&oi=ao

Introduction of the Tseng's group: Our research is wide-ranging, focusing primarily on the applications of metal nanoclusters, carbon dots, 2D materials and covalent organic frameworks to biosensors, bioimaging, surface-enhanced Raman and the removal of contaminants from water.


Research Topics

Nanomaterials, 

biosensors, 

bioimaging, 

water purification 

photo catalytic degradation

SERS


Honor

◇2008 Award for Outstanding Young Scholar, National Sun Yat-sen University
◇2009 Outstanding Young Investigator Award, the Chinese Chemical Society
◇2010 Mr. Wu Ta-you Memorial Award, National Science Council, Taiwan
◇2013 Award for Outstanding Scholar, National Sun Yat-sen University


Educational Background

◇Ph.D., Analytical Chemistry, National Taiwan University(1997-2002)
◇B.S., Fu Jen Catholic University(1994-1997)


Job Description

The candidate will focus on the design, synthesis, and performance optimization of luminescent nanoprobes, including ligand- and protein-stabilized gold nanoclusters (AuNCs) and carbonized polymer dots (CPDs), and will explore their structure–property relationships, including emission behaviors, charge characteristics, surface chemistry, stability, and reaction kinetics. The work will also involve constructing hybrid sensing materials by integrating nanoclusters or CPDs with selective recognition scaffolds such as covalent organic frameworks (COFs), metal–organic frameworks (MOFs), nanozyme-based composites, and molecularly imprinted polymers (MIPs), aiming to achieve improved selectivity, signal amplification, and real-sample compatibility. In addition, the student may participate in the development of dual-mode sensing strategies that combine fluorescence/phosphorescence with surface-enhanced Raman scattering (SERS), enabling mechanistic and quantitative interpretation of signal transduction pathways, including adsorption/desorption, charge transfer, energy transfer, and microenvironment-controlled emission enhancement. The student will be expected to conduct systematic experiments, perform comprehensive physicochemical characterization using spectroscopic and microscopic techniques, rigorously analyze data, and contribute to high-quality publications and international research collaborations.

Preferred Intern Educational Level

The most appropriate Preferred intern educational level is: Preferred: Master’s student (M.S.) or Ph.D. student (doctoral level)

 

Skill sets or Qualities

The student is expected to be proficient in laboratory practices and willing to work independently on nanomaterial synthesis, surface modification, and characterization. Experience with UV–vis spectroscopy, fluorescence/phosphorescence measurements, Raman/SERS analysis, and nanomaterial characterization methods (e.g., TEM, DLS, zeta potential, FTIR, XPS) is highly desirable. The candidate should demonstrate strong problem-solving skills, careful experimental design, and good data processing capability (Origin and/or Python). Strong scientific writing skills, teamwork spirit, and effective English communication are important for successful collaboration, report preparation, manuscript submission, and participation in international research activities.

Internship-related fee required by the school/institution

Interns who conduct their internship on campus must apply as visiting students at least 1 month before their arrival. They are required to pay the fees listed on this page 

<https://oia.nsysu.edu.tw/p/412-1308-20683.php?Lang=en> 

 and complete registration/leaving procedures. Please note that NSYSU does not provide on-campus housing for visiting students. Interns will have to look for off-campus housing by themselves. Off-campus housing resources can be found on this page

<https://oia.nsysu.edu.tw/p/412-1308-20683.php?Lang=en>