Our study focuses on investigating multifunctional role of blood-brain barrier/neurovascular unit (NVU) in human neurodevelopmental disorders and neurodegeneration disease, dynamic regulation of neuron, neuroglia cells and vessel necessitate a highly communicated in brain microenvironment. It's essential between the CNS and the peripheral circulatory system as a dynamic balance, including to nutrient transport and the barrier to potentially harmful subjects. This homeostatic condition of the cerebral microcirculation dependent on the " blood-brain barrier/neurovascular unit " (NVU), handle all of these functions. Besides, we have interest to investigate the mechanism of NVU dysregulation in metastatic brain tumor. Our team include four directions:

1. The multifunction role of blood-brain barrier/neurovascular unit in human neurodegeneration disease, such as Alzheimer’s disease (AD).
2. The molecular mechanism in neurovascular unit (NVU) of brain-specific metastasis in breast cancer.
3. Intracellular and Extracellular Model Establishment and Mechanistic Research in Cerebral Small Vessel Disease (CSVD)..
4. The multifunction role of blood-brain barrier/neurovascular unit in renal disease-induced brain injury.

Welcome to join our team!
Our study focuses on investigating multifunctional role of blood-brain barrier/neurovascular unit (NVU) in human neurodevelopmental disorders, neurodegeneration disease and metastatic brain tumor. Our team include four directions:

1. The multifunction role of blood-brain barrier/neurovascular unit in human neurodegeneration disease, such as Alzheimer’s disease (AD).
2. The molecular mechanism in neurovascular unit (NVU) of brain-specific metastasis in breast cancer.
3. Intracellular and Extracellular Model Establishment and Mechanistic Research in Cerebral Small Vessel Disease (CSVD).
4. The multifunction role of blood-brain barrier/neurovascular unit in renal disease-induced brain injury.