Fu Jen Catholic University

WML Lab

Wei-Min Liu
https://sites.google.com/view/wmllab/home

Research Field

Chemistry

Introduction

Principal Investigator, Group Leader

Prof. Wei-Min Liu is a well-trained chemist with a broad research background spanning multiple areas of chemical and biochemical research. His expertise includes the development of novel synthetic methodologies, the design and synthesis of antibacterial agents, protein expression and modification, and the application of paramagnetic NMR techniques to investigate interactions between proteins and their molecular partners, including small molecules and other proteins. Currently, his research focuses on molecular design, employing organic synthesis to construct innovative molecular architectures and to explore the functional properties of synthesized compounds for diverse applications, such as the targeting of specific biomolecules through fluorescent signaling and the development of molecular rotor–based photocatalysts for efficient reactive oxygen species (ROS) generation. In addition, his group is actively developing new synthetic methodologies, particularly those utilizing S-ylides and N-ylides for the efficient construction of heterocyclic frameworks.

We warmly invite motivated undergraduate, graduate, and postdoctoral researchers to join the WML Lab. Our group offers a dynamic and collaborative research environment at the interface of organic synthesis, chemical biology, and molecular design. Research opportunities span the development of new synthetic methodologies, functional fluorescent probes, molecular rotor–based photocatalysts for reactive oxygen species (ROS) generation, and the investigation of biomolecular interactions. Guided by the core values of the WML Lab—Wise, Motivated, and Logical—we foster sound judgment, a curiosity-driven approach, perseverance in overcoming challenges, and rigorous, logical scientific thinking.

WML LAB Core Values

Wise - The ability to make sound judgments, ask meaningful questions, and pursue scientific truth with humility. 
Motivated - Driven by curiosity, strengthened by perseverance through challenges, and inspired by a passion to move research forward. 
Logical - Guided by clear reasoning, rigorous experimentation, and reliable, reproducible conclusions.


Research Topics

WML Lab's research focus on developing new synthetic methods, photocatalyst for photodynamic therapy, and chemical tools for visualizing biomolecules of interest. 

1) Synthetic Methodologies: The application of Sulfonium ions

2) Development of NIR probes for Islet amyloid polypeptide

3) Development of NIR probes for Human Serum Albumin

4) Development of Molecular-Rotor Based Oxidase Mimics

We very welcome young talented students who are interested in the development of functional molecules in the biological area to pursue their academic goals in our team at FJCU.


Honor

2024 Fu Jen Catholic University NSTC Special Outstanding Talent Award

2023 Fu Jen Catholic University NSTC/MOST Special Outstanding Talent Award

2022 Fu Jen Catholic University 111 Academic Year - Teaching Excellence Award

2022 Fu Jen Catholic University Recruiting and Retaining Outstanding Talent Award

2008 48th National and Private High School Science Fair Excellent Work from Ministry of Education R. O. C.

2007 Outstanding Graduate Research Poster Award from Department of Chemistry, NTU (awarded to top 20% research excellence)

2007 Excellent Oral Presentation Award from Department of Chemistry, NTU (awarded for clarity of oral presentation)

2006 Excellent Organic Graduate Research Poster Award from Chinese Chemical Society (awarded to top 15% research posters nationwide)


Educational Background

Work and Research Experience

2025 – present   Professor. Fu Jen Catholic University, New Taipei City, Taiwan

08.2024 – present   Deputy Dean, Office of International Education

08.2023 – present Director of Academic Exchange Center & EU Center

2022 - 2025 Associate Professor, Fu Jen Catholic University, Taiwan

2016 - 2022 Assistant Professor, Fu Jen Catholic University, Taiwan

2015 - 2015 Researcher, Sunny Pharmatech., Taiwan

2014 - 2015 Postdoctoral researcher, Oxford University, U.K.

Education

2013 Ph.D. Leiden University, The Netherlands.

2007 M.A. National Taiwan University.

2005 B.A. National Taiwan Normal University.


Job Description

The intern who joins our research group will focus on either the development of novel synthetic methodologies or new fluorescent probes for detecting heavy metals. During the internship, you will learn synthetic skills, spectra analysis, and bioassay. Furthermore, you can also learn scientific writing skills and practice oral presentations.

Preferred Intern Educational Level

Background in Organic Chemistry, Analytical Chemistry, or related fields (Master’s students)

Strong interest in Chemical Biology, Bioorganic Chemistry, or the development of Synthetic Methodologies

Willingness to work independently and collaboratively in a research environment

Considering PhD studies in Taiwan in the near future

Skill sets or Qualities

Basic Organic synthetic skill, Data analysis (NMR, UV-Vis, IR, et. al spectra)