Taipei Medical University

Professor Lee Kuen-Haur Lab

Kuen-Haur Lee
https://crdd.tmu.edu.tw/team/content?type=1&id=31

Research Field

Medicine
Introduction

Name: Kuen-Haur Lee

ORCID: https://orcid.org/0000-0002-6354-3315

Drug Repurposing and Cancer Molecular Mechanism Lab

Member in Our Lab

PhD students-Taiwan students (2 students)

Research direction: Small molecule-induced endosomal escape of LNP-based siRNA by targeting the X-protein

Research direction: Genomics study for drug resistant of colorectal cancer

PhD students-International students (2 students)

Research direction: Identification the risk factors of EoCRC

Research direction: Investigation the functional role of CRNDE-regulated molecules or signaling in obesity- or diabetes-related EoCRC could provide novel insights to enhance targeted CRC cancer therapies

Master students-Taiwan students (1 students)

Research direction: Identification DEGs between MAFLD and CRC

Msater students-International students (2 students)

Research direction: Drug Repurposing of FXYD3 in pancreatic cancer

Research direction: Investigating the efficacy of the active ingredient of the natural pPlant feverfew - Parthenolide, in the obesity/diabetes and early onset colorectal cancer comorbidity

Research Topics

Research Interests

  • Signal transduction of tumor biology
  • Drug repurposing of cancer
  • The roles of miRNAs in cancer

Related Link

Honor
  • 112-115 National Science Council Integrated Project-Discussion on the regulation of pancreatic cancer metastasis and acidic microenvironment in the MIR31HG-miR-7-5p/miR-206-FXYD3 signaling pathway of early pancreatic cancer metastatic gene-FXYD3 Role (chief PI)
  • 110-112 National Science Council Individual Project - Study on the role and function of the acidic microenvironment induced by extracellular matrix collagen in promoting malignant bladder tumors (co-PI)
  • The fourth phase of the Cancer Research Plan of the Ministry of Health and Welfare in 2011-114 - focusing on translational medicine research on colorectal cancer (II) (co-PI)
  • 112 Taipei Medical University-Ministry of Education Deepening Program-The role of targeting MIR31HG/LncHIFCAR-miRNAs-mRNAs related molecular networks in pancreatic cancer (chief PI)
  • 111 Taipei Medical University-Ministry of Education Deepening Program - Research on the correlation between pancreatic cancer-specific miRNA and MIR31HG and the development of ncRNA therapies (PI)
Educational Background

Education

  • 2009 Ph.D. Institute of Basic Medical Sciences, National Cheng Kung University
  • 2004 MS. Institute of Biomedical Sciences, National Sun Yat-sen University
  • 2002 B.S. Department of Marine Biotechnology and Resources, National Sun Yat-sen University

Experience

  • 2023.03.14-2024.03.13 Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2022- Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2022- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2016-2022 Associate Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2018-2022 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2018- Director, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2017- Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2012 Assistant Research Fellow, Institute for Cancer Biology and Drug Discovery, Taipei Medical University
  • 2010-2012 Postdoctoral Fellow in Division of Medicinal Chemistry, Ohio State University, USA