I am a physician-scientist and Distinguished Investigator and Director of the Immunology Research Center at the National Health Research Institutes, Taiwan. I earned my M.D. from National Yang-Ming

University and my D.Phil. from the University of Oxford, followed by postdoctoral training at Stanford University. My career connects fundamental immunology with the development of new approaches to

treating human disease. Academic background.

1. My laboratory investigates how immune receptors recognize pathogens and regulate inflammation, with particular interests in C-type lectins, glycan recognition, and immune checkpoints. Our

research has helped define the roles of CLEC5A and CLEC2 in infection-associated inflammation and identified Siglec-3/CD33 as an immune checkpoint in hepatitis B virus infection. We seek to

translate these discoveries into therapeutic antibodies and immunomodulatory strategies for infectious diseases, cancer, and inflammatory disorders. Our interests also extend to tissue repair and

regeneration. Research profile · Research contributions. Through the IIPP, I welcome motivated students who are curious about how the immune system protects the body—and how dysregulated

immune responses contribute to disease. Potential research topics include host–pathogen interactions, immune receptor signaling, and the development of therapeutic approaches. My aim is to help

students strengthen their scientific reasoning, learn to formulate meaningful research questions, and connect experimental findings with biomedical challenges. I look forward to exchanging ideas

with students from diverse backgrounds and supporting their development as researchers through an engaging research experience in Taiwan.

2. New field: Regenerative Immunology and Aesthetic Applications ; Another major focus of my laboratory is regenerative immunology, including our work on decoy receptor 3 (DcR3) and IMRC01. We

aim to reprogram macrophages toward tissue-repairing and inflammation-resolving states, harnessing their capacity to restore tissue homeostasis. Through this approach, we seek to promote

wound healing and hair growth, reduce fibrosis, and support the resolution of inflammation. This research connects