Bacterial Pathogenesis and Therapeutics Laboratory
Research Field
Dr. Jenn-Wei Chen is an Associate Professor in the Department of Microbiology and Immunology at National Cheng Kung University. He obtained his Ph.D. in Microbiology and Immunology from National Yang-Ming University in 2006. Following his doctoral training, he conducted postdoctoral research at the National University of Singapore and Cornell University, where he further developed his expertise in bacterial pathogenesis and host–microbe interactions.
Dr. Chen joined National Cheng Kung University in 2013 and has been serving as a faculty member since then, being promoted to Associate Professor in 2022. His research primarily focuses on bacteriology, microbiota research, and the molecular mechanisms underlying host–pathogen interactions. His work integrates proteomics and transcriptomics to investigate bacterial virulence, antimicrobial resistance, and the role of the microbiota in human health and disease.
My laboratory is located on the 11th floor of the College of Medicine building at National Cheng Kung University.
Currently, the lab consists of one Ph.D. student and four master’s students. It is equipped with facilities for working with general pathogenic bacteria and anaerobic bacteria, as well as for Caenorhabditis elegans experiments and cell culture. Additionally, the laboratory performs molecular biology techniques and basic experiments involving the purification of recombinant proteins. The laboratory currently holds a weekly progress report meeting.
My research program also explores translational applications, including the development of novel therapeutic strategies such as vaccines and microbiota-based interventions for infectious and inflammatory diseases. I have led multiple research projects as principal investigator, including studies on Clostridioides difficile infection, microbiota–host interactions, and probiotic-based therapies. I have contributed to a growing body of scientific literature in microbiology and immunology, and continue to advance understanding of microbial pathogenesis and its clinical implications.
*JDIP scholarship award. The 10th International Colloquium for Paratuberculosis (ICP). 2009
*JDIP travel award. The Johne's Disease Integrated Program (JDIP) 4th Annual Conference. 2008
Ph. D., Institute of Microbiology and Immunology, National Yang-Ming University, Taiwan
M. Sc., Institute of Microbiology and Immunology, National Yang-Ming University, Taiwan