National Dong Hwa University

Microfluidics and Cell Biology Lab

Han-Yun Hsieh
https://sys.ndhu.edu.tw/RD/TeacherTreasury/tlist.aspx?tcher=13501

Research Field

Emerging/Other Fields

Introduction

I am currently an Assistant Professor in the Department of Biochemistry and Molecular Medicine at National Dong Hwa University, Taiwan. I received my Ph.D. in June 2020 from the Graduate School of Medicine at Osaka University, Japan. After completing my doctoral degree, I worked as a postdoctoral researcher at the Institute of Applied Mechanics, National Taiwan University. I was also invited by Hiroshima University to serve as a specially appointed assistant professor for the Japan–Taiwan Women Researchers International Collaboration Program (2021–2023).

In the future, I aim to further expand my research toward the field of precision biomedicine, integrating microfluidic technologies with disease modeling and mechanistic studies.

Our laboratory focuses on integrating microfluidic technology, vascular biology, and molecular medicine to investigate disease mechanisms and develop advanced biomedical models.

Our research aims to build biomimetic microfluidic systems that replicate physiological environments in vitro. By combining microfluidics with cell biology and molecular analysis, we develop experimental platforms to study complex biological processes that are difficult to observe in conventional cell culture systems.

Our laboratory emphasizes interdisciplinary collaboration, integrating approaches from biomedical engineering, molecular biology, and translational medicine. We are committed to training students with both strong experimental skills and critical scientific thinking, preparing them for future careers in biomedical research and biotechnology.


Research Topics

Research Topics:

(1) Microfluidic thrombosis and vascular disease models

(2) PM2.5-induced mitochondrial dysfunction and oxidative stress

(3) Microfluidic disease-on-chip platforms for precision biomedicine


Honor

Consumer Electronics Show (CES) 2025 Innovation Award: Laser-Induced Thrombosis Chip Integrated System


Educational Background

Ph.D. Graduate School of Medicine, Osaka University, Japan (2020)


Job Description

Through hands-on experience in microfluidic device fabrication, biomaterials integration, and advanced cellular assays, participants will acquire essential experimental skills and develop critical thinking in experimental design and data interpretation. This training environment enables students to contribute to cutting-edge research at the interface of biomedical engineering, translational medicine, and sustainable biomaterial innovation.

Preferred Intern Educational Level

To support these research efforts, we warmly invite undergraduate and master’s students with interests in microfluidic systems, biomaterials, and disease-on-chip technologies to join our laboratory. Applicants should possess strong communication skills, the ability to work effectively in interdisciplinary teams, and a solid foundation in basic biomedical sciences, including cell biology and bioengineering concepts.

Skill sets or Qualities

Students interested in vascular biology, thrombosis-on-chip systems, environmental health, or multi-cancer disease modeling are particularly encouraged to apply.

Prior experience in microfluidic fabrication, cell culture, or bioanalytical techniques will be considered an advantage.