National Taiwan University

Nutrition and Metabolites

Louis Grillet
https://metabolitesandplantnutrition.com/

Research Field

Biology

Introduction

I am French national living in Taiwan since 2013. I am specialized in plant sciences: I originally studied seed and plant production and then moved to biochemistry and molecular biology. I studied in various universities in France, including Angers, Nantes,  Rennes and Montpellier, and I also spent some of my Bachelor years in the Netherlands at Dronten CAH and Amsterdam VU. I moved to Taiwan for a post-doc after passing my PhD in Montpellier, and obtained a position at National Taiwan University in 2020. 

As sessile organisms, plants cannot move to escape adverse conditions. They instead attempt to modify their immediate environment by secreting metabolites. A typical example of this lies in the nutrition in essential trace metal elements such as iron, zinc and copper. While these elements are generally present in sufficient amount in soils, their solubility is low, causing problems of deficiencies that are deleterious for crop yield. As an adaptation, plants evolved to secrete molecules that can enhance the bioavailability of these elements, in particular iron. The ability of plants to efficiently acquire iron at high pH is the major determinant of their calcicole behavior. Interestingly, the inability to grow in such conditions can be rescued by the presence of a calcicole neighboring plant, demonstrating that in these iron-scarce conditions, plants collaborate rather than compete. We are interested in understanding the physiological and biochemical effect of root-secreted molecules, a small subset of the hundreds thousands metabolites produced by plants.


Research Topics

We study the effect of various molecules on the plant's behavior with an emphasis on plant nutrition. We try to discover novel effects of known molecules and to understand the mode of action of these molecules.

We therefore have two main research projects:

1- testing molecules on plants and measuring the molecular responses of the plants

2- applying molecules to plants lacking certain signaling pathways to find out how a given molecule affects plant behavior

 


Honor

Excellent Teacher of the College of Bioresources and Agriculture 2024 and Excellent Teacher for English-taught courses in 2025


Educational Background

2009 - 2012 Ph.D. in Integrative Plant Biology (Laboratory of Plant Molecular Biology and Physiology, BPMP, INRA/Montpellier Supagro, France). Thesis: Speciation, transport and subcellular localization of iron in Pisum sativum and Arabidopsis thaliana developing seeds. 

2007 - 2009 Master's Degree in Plant Biology (University of Rennes, France)

2006 - 2007 Bachelor’s Degree in Biology – Biochemistry (University of Nantes, France)

2004 - 2006 Bachelor’s Degree in Plant Production, breeding and experimentation (ESA Angers, France and CAH Dronten, The Netherlands)


Job Description

We will also study the response of plants defective in various signaling pathways to gain insights on the mode of action of these plant-secreted molecules. The mutants will be included together with healthy wild-type plants.

Preferred Intern Educational Level

Senior Bachelor students or Master students

Skill sets or Qualities

Basic knowledge of plant biology, molecular biology and biochemistry is required

Job Description

The methods employed will include spectrophotometric quantitification of iron and chlorophyll, measurements of gene expression, and confocal microscopy.

Preferred Intern Educational Level

Bachelor or Master students in the field of biology, plant sciences or biotechnology

Skill sets or Qualities

Basic knowledge of molecular biology and plant physiology.