Chang Gung University

Pharmaceutics Laboratory

Jia-You Fang
https://jiayoufang.pixnet.net/blog/posts/14016902871

Research Field

Biology

Introduction

Distinguished Professor Jia-You Fang, now work in Graduate Institute of Natural Products, Chang Gung University. He has established a research team comprising domestic and international scholars. The team primarily focuses on drug formulation design and drug delivery targets, particularly the research and development of nanocarriers for drugs and active ingredients, and natural actives for mainly regulating and treating immune-inflammatory diseases. Additionally, Professor Fang has established animal evaluation platforms for various diseases, which are utilized by pharmaceutical industries to verify the effectiveness and safety of their products. These animal models established in the laboratory include sepsis, methicillin-resistant Staphylococcus aureus (MRSA)-induced pneumonia, acute lung injury, liver fibrosis, psoriasis, atopic dermatitis, and cutaneous photoaging. Professor Fang has published a total of 373 SCI journal papers, cited more than 17,000 times (Scopus), with an h-index of 71 (Scopus). For three consecutive years, Professor Fang has been recognized among the top 2% of the world's top scientists according to Stanford University statistics. Based on these data, the United Daily News included Professor Fang in the list of Taiwan’s top 35 clinical and basic medical researchers, ranking 23rd for two consecutive years. In 2023, Professor Fang received the "Outstanding Contribution Award for Domestic Medical Research Achievements to the Development of Medical Technology, National Health, National Society and Industrial Development" at the 33rd Wang Ming-Ning Award. Only three scholars in Taiwan received this award. In recent years, Professor Fang has actively carried out industry-university cooperation projects. To date, 31 industry-university cooperation projects have been implemented. Professor Fang holds seven US or Taiwan patents, mainly for developing new indications of natural products and designing nanoformulations. Professor Fang has long served as a review committee member for pharmacy-related fields in the Ministry of Economic Affairs, Ministry of Health and Welfare, and Ministry of Education, assisting the government in promoting research on pharmacy and traditional Chinese medicine. Additionally, Professor Fang serves as a consultant to the Medical and Pharmaceutical Industry Technology and Development Center. In this corporate consortium, he guides the unit plans and supervises its progress.

In Japan, pharmaceutical research falls under the field of medical pharmacy, while in Europe and the United States, it is considered part of pharmaceutical company research and development. Its essence lies in using newly designed prescriptions, additives, or materials to maximize the pharmacological activity of a given drug, minimize its toxicity and side effects, or prolong its retention time in the body. Its significance lies in making clinical medication safer and more effective, thereby improving patient compliance. Pharmaceutical science is considered a downstream process in drug development within pharmaceutical research; it is an applied science. The main work of this laboratory is to design new prescriptions for drugs and explore their ability and extent to improve the shortcomings of traditional dosage forms.


Research Topics
  1. Drug delivery through skin
  2. Nanocarrier design for treating skin inflammation diseases
  3. Natural product development for treating autoimmune disorders
  4. The development of prebiotics for skin health
  5. Laser-assisted drug absorption
  6. Gene delivery and therapy
  7. Nanoparticle targeting for treating bacteremia and sepsis

Honor
2010~2025Subsidy to Reward The Special Outstanding Scholars in UniversitiesNational Science and Technology Council
2024Outstanding Research Award for Academic PapersThe Natural Medicine Society of Taiwan
202428th Distinguished AlumniKaohsiung Medical University
202333rd Wang Ming-Ning AwardWang Ming-Ning Memorial Foundation
202219th National Innovation AwardInstitute for Biotechnology and Medicine Industry
2020Outstanding Research Award for Academic Papers The Natural Medicine Society of Taiwan
2018Outstanding Teacher Research AwardChang Gung University
2017Conference Poster Excellence Award6th Euro-Asian Association of Dermatovenereologists Congress
2015Outstanding Paper AwardChinese Society of Cosmetic Surgery and Anti-Aging Medicine
2011 & 2014Outstanding Teacher Research AwardChang Gung Unversity of Science and Technology
20136th Distinguished AlumniCollege of Pharmacy, Kaohsiung Medical University
2009Outstanding Poster Award10th International Congress of Dermatology
2005 & 2006R&D Paper Excellence AwardFormosa Plastics Corporation Enterprise Applied Technology Seminar

Educational Background

Ph.D, Kaohsiung Medical University