Organic Synthesis Laboratory
Research Field
Che-Sheng was born and raised in Taiwan. He began his undergraduate studies at the Chia Nan University of Pharmacy & Science in Tainan under the guidance of Prof. Huo-Mu Taic. After completing his bachelor’s degree, he continued his graduate education at National Chung Cheng University (NCCU), where he pursued a research-based master’s degree in the laboratory of Prof. Bor-Cherng Hong.
In the fall of 2011, Che-Sheng entered the doctoral program at National Taiwan University (NTU) under the supervision of Prof. Jim-Min Fang. During his Ph.D. training, he successfully accomplished the total synthesis of antroquinonol A and D.
Following his doctoral studies, Che-Sheng began postdoctoral research in the fall of 2016 at Academia Sinica in the laboratory of Prof. Rong-Jie Chein, focusing on organocatalysis. In the fall of 2018, he joined the University of Vienna as a postdoctoral researcher in the laboratory of Prof. Nuno Maulide, working on hydroaminoalkylation of unsaturated hydrocarbons. In the winter of 2019, he moved to Purdue University to continue his postdoctoral training in the laboratory of Prof. Arun Ghosh, where he contributed to the total synthesis of EBC-23.
In the spring of 2021, Che-Sheng returned to Academia Sinica to pursue further postdoctoral studies in the laboratory of Prof. Chi-Huey Wong, focusing on complex molecule synthesis. In August 2022, he joined Fu Jen Catholic University as an Assistant Professor in the Department of Chemistry, where his research group investigates the synthesis of complex molecules and the development of innovative organic synthetic methodologies.
Our laboratory focuses on organic synthesis chemistry as the core research area, dedicated to exploring novel reaction methodologies and catalytic technologies, and applying these advances to the construction of complex, high-value molecules. With the gradual depletion of natural resources, the development of sustainable chemistry has become a global trend, and our research directions align closely with this need.
Research Focus
Development and Applications of Hypervalent Iodine Reagents
Investigating the reactivity of hypervalent iodine reagents.
Establishing their new applications in catalytic reactions.
Using them as a starting point for novel synthetic methodologies.
Innovative Synthetic Methodologies
Developing highly efficient organic synthesis pathways.
Exploring new approaches to replace or optimize existing technologies.
Targeting sustainable energy and green chemistry.
Complex Molecule Synthesis
Integrating the above research outcomes into the synthesis of natural products and pharmaceutical molecules.
Constructing molecular architectures with biological activity and application potential.
Vision
Through the development of catalytic reactions and innovative methodologies, we aim to establish efficient synthetic strategies and apply them to industrial and pharmaceutical fields. Our ultimate goal is to cultivate young chemists with independent research capabilities and to continuously achieve breakthroughs in sustainable chemistry and molecular innovation.
With the rapid increase in population, natural resources are being depleted at an accelerated pace, which has begun to affect the progress of science, industry, and medicine, and may eventually limit the quality of human life. Organic synthesis, as a fundamental science, plays a crucial role in advancing developments in both industry and medicine. As natural resources become increasingly constrained, chemists have turned their attention toward the development of sustainable energy technologies, particularly through catalytic reactions. At the same time, the search for new technologies to replace or optimize existing ones has attracted significant interest, driving the exploration of novel synthetic methodologies. Together, these two research directions promote the efficient construction of complex, high-value molecules.
Our laboratory currently focuses on high-valent iodine reagents as the starting point of our research, investigating their reactivity in catalytic transformations and the development of new methodologies. Ultimately, we aim to integrate these two areas of study and apply the results to the synthesis of complex molecular architectures.
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- National Taiwan University (NTU), Taiwan. Ph.D. in Department of Chemistry. (Sep. 2011- Jun. 2015)
- National Chung Cheng University (NCCU), Taiwan. M.S. in Department of Chemistry and Biochemistry. (Sep. 2009-Jun. 2011)
- Chia Nan University of Pharmacy & Science, Taiwan. B.S. in Department of Medicinal Chemistry. (Sep. 2005-Jun. 2009)