You‑Yin Chen serves a dual role as Principal Investigator of the NeuroTechnology Laboratory (NTK Lab) and the Computational Intelligence in Biomedical Data Science Lab (CIBDS Lab) at National Yang Ming Chiao Tung University. His research leadership uniquely integrates fundamental neurotechnology innovation with regulatory-grade validation and international translation, bridging the full pathway from neural systems research to deployable healthcare solutions.

At NTK Lab, Dr. Chen leads research on neural decoding, neuromodulation, brain-computer interfaces, and advanced neural interfaces, with a strong emphasis on circuit- and network-level mechanisms. His work spans MRI-compatible neural devices, multimodal neuroimaging, and closed-loop neurotechnology platforms for studying and modulating brain networks in neurological and neuropsychiatric disorders. These efforts establish clinically meaningful, pre-translational testbeds that connect neural dynamics with therapeutic and assistive applications.

Complementing this foundational research, Dr. Chen directs CIBDS Lab as an ISO/IEC 17025–accredited independent third-party testing and validation laboratory, providing impartial verification of biomedical devices and medical software. Under his leadership, CIBDS Lab supports functional testing, AI software validation, and regulatory compliance for ECG, PPG, EEG, wearable systems, and hearing devices, including Taiwan’s first and only accredited professional hearing aid testing facility.

By unifying neurotechnology development with regulatory science and international linkage, Dr. Chen enables a seamless translation framework that aligns innovation, clinical validation, and global deployment. This dual-lab structure positions his research program as a strategic bridge between neuroscience, engineering, policy, and healthcare ecosystems worldwide.

1.  NTK Lab Overview (https://neurotech.lab.nycu.edu.tw/)

The NeuroTechnology Laboratory (NTK Lab) develops next-generation neurotechnologies for decoding and modulating brain function across multiple spatial and temporal scales. Integrating neuroscience, biomedical engineering, signal processing, machine learning, and neurophysics, the lab investigates how neural circuits and large-scale brain networks encode information and how disrupted communication and synchronization contribute to neurological and neuropsychiatric disorders.

NTK Lab advances neural recording and neuromodulation platforms, including multichannel electrophysiology, optogenetic and photonic interfaces, DBS-based neuromodulation, and brain-computer interface systems. These technologies are combined with biophysically informed and data-driven decoding frameworks to extract reliable, temporally structured neural representations.

Building on these foundations, the lab extends neural decoding and modulation toward clinical pre-translational neurotechnology. By integrating brain and neuromuscular signals with digital twin modeling and wearable assistive systems, NTK Lab establishes closed-loop platforms for studying sensorimotor adaptation, human-machine interaction, and the durability of neural control, bridging fundamental neuroscience with assistive and therapeutic applications.

2. Computational Intelligence in Biomedical Data Science Lab (CIBDS Lab, https://biomedai.lab.nycu.edu.tw)

The Computational Intelligence in Biomedical Data Science Lab (CIBDS Lab) serves as a strategic hub for the international translation of biomedical AI and medical device technologies. Operating as an ISO/IEC 17025–accredited independent third-party testing laboratory, CIBDS Lab provides impartial, standards-compliant validation of biomedical devices and medical software, supporting global regulatory and market-entry requirements.

The lab offers internationally aligned functional testing and verification services for ECG, PPG, EEG, wearable biomedical devices, and AI-based medical software. Notably, CIBDS Lab established the first and currently the only accredited professional hearing aid testing laboratory in Taiwan, providing electroacoustic evaluations in compliance with IEC 60118 and ANSI S3.22 standards. This capability supports national policy development, clinical quality assurance, and international product certification.

Beyond testing, CIBDS Lab delivers end-to-end translational support, including feasibility assessment, prototype evaluation, clinical study design, regulatory strategy, and post-market performance analysis. This integrated approach enables international partners to reduce regulatory risk and accelerate time-to-market.

CIBDS Lab maintains close collaborations with global industry leaders and national research organizations, including ASUS, Garmin, Microlife, Quanta Computer, as well as Industrial Technology Research Institute, Institute for Information Industry, and Metal Industries Research & Development Centre.

Internationally, the lab actively links Taiwanese innovators with overseas accelerators, clinical validation hubs, and investment networks, enabling effective engagement with U.S. and global healthcare ecosystems. Through regulatory rigor, clinical relevance, and cross-border connectivity, CIBDS Lab strengthens the global deployment of trustworthy biomedical AI technologies.