Academia Sinica

3D Mechanobiology Lab

Keng-hui Lin
http://www.phys.sinica.edu.tw/~softlab

Research Field

Physics

Introduction

I received PhD from Dept. of Physics and Astronomy, University of Pennsylvania, USA. I am trained as a soft matter physicist. Afterwards, I performed the postdoctoral research at Dept. of Chemistry and Chemical Biology at Harvard University. Upon joining Academia Sinica, I was intrigued that how cells sense the third-dimensionality is an open question. Gradually, I shift the research focus toward the biological physics. 

 

My lab is very interdisciplinary where we utilize tools from many disciplines such as advanced optical microscopy, molecular biology, physical modeling and material fabrication. My lab have the confocal microscope, cell culture room, simple micro-fabrication facility, and computer workstation loaded with high-end GPU card.


Research Topics

Currently, my lab has two research topics. (i) Investigating mechanobiology in 3D to understand how cells sense the third dimensionality. (ii) Investigating mechanobiology in zebrafish to understand the organization of epithelial sheet. My lab welcome people who are open-minded and self-motivated to explore their curiosity in the realm of cell biology through the lens of physics.


Honor

Awards for the PI

  • Academia Sinica Presidential Scholars Program (2025-2027).
  • National Innovation Award (2016)
  • Academia Sinica Career Development Award (2014).
  • Taiwan Outstanding Young Female Scientist Award (2013).
  • TWAS Young Affiliates (2011).
  • Elias Burstein Award (2002), for outstanding thesis in condensed matter physics.
  • Robert E. Davis Student Travel Award from AWIS-PHL (1999).
  • Dr. C. C. Samuel Ting Scholarship (1992-1995).
  • National Gifted Student in Physical Sciences Scholarship (1991-1995).
  • Skipped the last year in high school and entered Dept. of Physics, NTU as the first choice.

 


Educational Background
Summer Course: “Physiology,” Marine Biological Laboratory, Woods Hole, MA, USA.2009

PhD in Physics, Univ. of Pennsylvania, Philadelphia, PA, USA.

Thesis Advisor: Prof. Arjun G. Yodh.

Thesis: Entropically Driven Colloidal Crystallization and Interaction

1996-2002

BS in Physics, NTU, Taipei, Taiwan.

Skipped last year in high school and entered NTU Physics as the first choice

1991-1995