Taipei Medical University

Integrated Bio Microfluidics and System Analysis Lab

Li-Chern Pan
https://tmu.pure.elsevier.com/en/persons/li-chern-pan-2

Research Field

Medicine

Introduction

My interdisciplinary expertise bridges biomedical engineering, mechatronics, and reproductive medicine. At TMU, I leads advanced projects on microfluidic biochips and biomedical devices designed to isolate and analyze rare biological entities—from circulating tumor cells to high-quality sperm—for clinical and research applications .

Key Research Interests:

  • Bio‑Mechatronics & Medical Electronics: Developing intelligent systems that integrate microscale robotics, electronics, and optics .
  • Microfluidic Biochips for Diagnostics: Innovating biochip platforms for cell sorting (e.g., circulating tumor cells, progressive sperm) using gentle, damage-minimizing methods with FDA‑compatible glass-based device
  • Translational Biomedical Engineering: Focusing on portability and clinical adoption, steering MEMS-based chip technologies toward real-world diagnostics .

Our lab's work exemplifies TMU’s commitment to merging cutting-edge engineering with clinical challenges, with a strong translational vision—from lab-scale prototypes to FDA-compatible, patient-ready solutions in fertility and oncology diagnostics.

Selected Projects & Achievements includes:

  • High‑throughput sperm sorting systems for couples facing infertility
  • Auto-adherence microchips to isolate circulating tumor cells in collaboration with biological and medical teams
  • FDA‑compliant microfluidic coagulometer chips, integrating 2D materials and intelligent MEMS for real-time blood coagulation monitoring


Research Topics
  • Bio Mechatronics
  • Reproductive medicine
  • Biomedical engineering
  • Medical electronics

Honor
  • 2014  11th National Innovation Award
  • 2020 17th National Innovation Award

Educational Background
  • 1990.09-1996.06 Ph.D, Department of biomedical engineering, Rutgers, The State University of New Jersey, NJ, USA
  • 1988.09-1990.06 M.S., Department of electrical engineering, Rutgers, The State University of New Jersey, NJ, USA
  • 1984.09-1986.06 M.S., Department of Physics, National Central University, Taiwan
  • 1980.09-1984.06 B.S., Department of Physics, Fu Jen Catholic University, Taiwan

Job Description

Applicants are expected to show strong intension in understanding and improve techniques for the detection and characterization of such rare cells, thereby facilitating progress in diagnostics and therapeutic development.

Preferred Intern Education Level

Applicants are expected to be at least sophomores or higher in college, enrolled in programs focused on life sciences and/or biomedical engineering.

Skill sets or Qualities

  • Basic laboratory techniques — experience with pipetting, sample preparation, sterile technique, etc.
  • Microfluidics knowledge — understanding of microfluidic principles and device operation (preferred but not required)
  • Biomedical device familiarity — exposure to biomedical sensors, devices, or related instrumentation
  • Cell biology background — knowledge of stem cells, germ cells, or rare cell types
  • Data analysis skills — proficiency in data collection, statistical analysis, and visualization (e.g., Excel, MATLAB, Python)
  • Programming ability — familiarity with programming or scripting languages for data processing (e.g., Python, MATLAB) is a plus
  • Technical communication — good scientific writing and presentation skills