National Cheng Kuan University

Medical Ultrasound Imaging Lab

Chih-Chung Huang
https://bme.ncku.edu.tw/p/404-1101-247560.php?Lang=zh-tw

Research Field

Medical Engineering

Introduction

Chih-Chung Huang was born in 1978, Taiwan. He received the B.S., M.S., and Ph.D. degrees in Biomedical Engineering from Chung Yuan Christian University, Chung-Li, Taiwan, in 2002, 2003, and 2007. From 2006 to 2007, he worked at NIH Resource Center for Medical Ultrasonic Transducer Technology at the University of Southern California, Los Angeles, USA as a Visiting Researcher where he was engaged in research of high frequency ultrasound imaging and development of new acoustic methods for cataract diagnosis. In 2008, he joined the Department of Electrical Engineering, Fu Jen Catholic University, Taiwan as an Assistant Professor. In 2012, Dr. Huang was promoted as an Associate Professor. In 2013, he joined the Department of Biomedical Engineering, National Cheng Kung University, Taiwan. Currently, he is a Distinguished Professor at Department of Biomedical Engineering. Dr. Huang was the Deputy Director of Medical Device Innovation Center, the Deputy Director of Technology Transfer & Business Incubation Center, the Strategic Planning Division Director of Research & Services Headquarters at National Cheng Kung University, Taiwan. He was the Secretary General of Taiwanese Society of Biomedical Engineering. He was a visiting professor in the NC State University, Department of MAE, NC, USA from 2021/08 to 2022/08. His research interests include ultrasonic tissue characterization, blood flow measurement, high frequency ultrasound, and ultrasonic instrument for medical applications, etc. Dr. Huang was selected as a member of IFMBE Asia-Pacific Research Networking Fellowship as well as the ordinary member of CoS representative of Taiwanese Society of Biomedical Engineering of IFMBE affiliated Society. Dr. Huang is an associate editor for Medical Physics and Journal of Medical and Biological Engineering, guest editor for IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. He is a senior member of IEEE as well as the TPC member of IEEE IUS.

My research focuses on the Biomedical Ultrasound Imaging, including developments of both hardware and software for high frequency ultrasound imaging systems, deep learning technology for medical ultrasound imaging, ultrafast ultrasound imaging, high frequency ultrasound Doppler technology for blood flow measurement, novel ultrasound elastography technology, high frequency ultrasonic tissue characterization, and ultrasound for neuroscience applications. I would like to provide the new generation medical diagnostic devices for compensating the deficiencies of existing medical ultrasound imaging technology by multidisciplinary integration of engineering and medical diagnosis. One of my important topics is the novel high resolution ultrasound bio‐microscopy for neuroscience applications, which combines with high frequency ultrasound duplex imaging and high-resolution ultrasound elastography technology, which will be useful for tissue characteristics of human in clinical and small animal in pre‐clinical study. All my research fields provide the complete non‐invasive solutions for gene research, cancer study, ophthalmology, skin, cardiovascular disease, and neuroscience diagnosis. The detailed descriptions of my specific research interests are as follows: 


Research Topics

High resolution brain ultrasound imaging for neurodegenerative disease

文字方塊:  
High resolution ultrasound blood imaging for mice brain (Huang Lab)
 
High resolution ultrasound elastography for mice brain (Huang Lab)
The clinical symptom of Alzheimer’s disease (AD) includes a progressive decline of memory function. A high density of neuritic plaques, neurofibrillary tangles, and vascular amyloid (Aβ) is a characteristic neuropathological marker of AD. Plaques and tangles in the neuropil may affect neuronal function and contribute to the neuronal damage; however, it is unclear whether their incidence correlates with the clinical signs and symptoms of cognitive impairment characteristic of the disease. Substantial evidence from epidemiological, pathological, and clinical reports suggests that vascular factors are critical in the pathogenesis of AD, and changes in blood flow are currently the most reliable indicators of the disease. Currently, AD mouse is a good small animal model for AD pre‐clinical studies, however, there is no suitable high resolution imaging system for detecting the vascular properties of mouse. Therefore, I am going to develop a high frequency ultrahigh frame rate ultrasound imaging array system for monitoring the variations of brain circulation, including the density of vessel, the atherosclerosis of brain, and brain activation. Then, I build a high-resolution mouse brain shear wave elastography for detecting the viscoelastic properties of AD mouse brain tissue and try the find the relationship between brain mechanical properties and neuritic plaques and neurofibrillary. Finally, high frequency ultrahigh frame rate Doppler imaging and high resolution elastography will be applied to AD mouse to measure the density of vessel, the atherosclerosis of brain, brain activation, and brain elasticity during AD. The experimental results will compare to histo‐chemistry results for the future pre‐clinical studies to explore brain and cerebral vascular elasticity for fiber tangle with amyloid plaques affects the nervous foundation. 

 

 


Honor

2025 Outstanding Teaching Award, National Cheng Kung University, Taiwan

2024 Outstanding Poster Paper Award, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Outstanding Poster Paper Award, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Outstanding Poster Paper Award, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Excellent Poster Paper Award, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Excellent Poster Paper Award, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Excellent Oral Paper Award, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Outstanding Oral Paper Award, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 IEEE TMI Distinguished Reviewer, Silver Level Award

2023 IEEE Tainan Section Outstanding Technical Achievement Award

2023 Ministry of Science and Technology Future Tech Award, Taiwan

2022 Ministry of Science and Technology Future Tech Award, Taiwan

2021 Excellent Research Award, Engineering College, National Cheng Kung University, Taiwan

2021 Best paper award, 2021 International Forum on Medical Imaging in Asia (IFMIA), Taiwan

2020 Silver Medal Award, Point-of-Care Ultrasound Innovation Competition, Taiwan Society of Ultrasound in Medicine, Taiwan.

2020 Honorable Mention Award, Point-of-Care Ultrasound Innovation Competition, Taiwan Society of Ultrasound in Medicine, Taiwan.

2020 Ministry of Science and Technology Future Tech Award, Taiwan

2019 Best Conference Paper Award, 2019 IEEE Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability, Okinawa, Japan.

2018 Best Oral Presentation Award, 3rd Global Conference on Biomedical Engineering (GCBME 2018), Taoyuan, Taiwan.

2017 The Best Annual Paper Award, Journal of Medical and Biological Engineering (SCI)

2017 Best Presentation Award, 2017 Engineering Medical Innovation Global Competition, Taipei, Taiwan

2016 Rising Star Award, College of Engineering, National Cheng Kung University, Taiwan

2015 Certificate High Distinction, Symposium of Annual Conference of the Biomedical Engineering Society Poster Paper Competition, Taiwan 

2015 Distinction Certificate, Young Scholar Innovation Competition, Comprehensive University System of Taiwan 

2015 Ministry of Science and Technology Research Project for Excellent Young Scholars (2015–2018)

2014 Best paper award, 1st Global Conference on Biomedical Engineering (GCBME 2014) / 9th Asian-Pacific Conference on Medical and Biological Engineering, Taiwan.

2014 Honorable Mention Award, 1st Global Conference on Biomedical Engineering (GCBME 2014) / 9th Asian-Pacific Conference on Medical and Biological Engineering, Taiwan.

2014 Best Potentiality Award, Biomedical Engineering Innovation Competition, Taiwan

2013 Certificate High Distinction, Symposium of Annual Conference of the Biomedical Engineering Society Oral Paper Competition, Taiwan 

2013 Certificate High Distinction, Symposium of Annual Conference of the Biomedical Engineering Society Poster Paper Competition, Taiwan

2013 Honorable Mention Award, Symposium of Annual Conference of the Biomedical Engineering Society Poster Paper Competition, Taiwan

2012 Ministry of Science and Technology Research Project for Excellent Young Scholars (2012–2015)

2012 JMBE Annual Excellent Paper Award, Taiwan

2012 Certificate High Distinction, Symposium of Annual Conference of the Biomedical Engineering Society Oral Paper Competition, Taiwan 

2012 Honorable Mention Award, Symposium of Annual Conference of the Biomedical Engineering Society Oral Paper Competition, Taiwan

2012 Honorable Mention Award, Symposium of Annual Conference of the Biomedical Engineering Society Oral Paper Competition, Taiwan

2012 The Best Advisor Award, Creative Design and Implementation Competition on Biomedical Engineering, Taiwan

2012 Honorable Mention Award, Creative Design and Implementation Competition on Biomedical Engineering, Taiwan

2011 Outstanding research Award, Fu Jen Catholic University

2011 Honorable Mention Award, Symposium of Annual Conference of the Biomedical Engineering Society Oral Paper Competition, Taiwan

2010 Certificate High Distinction, Symposium of Annual Conference of the Biomedical Engineering Society Oral Paper Competition, Taiwan

2010 Honorable Mention Award, Symposium of Annual Conference of the Biomedical Engineering Society Oral Paper Competition, Taiwan

2010 Certificate High Distinction, Symposium of Annual Conference of the Biomedical Engineering Society Poster Paper Competition, Taiwan 

2009 Outstanding research Award, Fu Jen Catholic University

2009 Honorable Mention Award, Symposium of Annual Conference of the Biomedical Engineering Society Student Paper Competition, Taiwan

2008 Outstanding paper Award, 13th International Conference on BioMedical Engineering, Singapore

 

Academic Activities                                                                              

2025 Doctorate Examination Committee, Monash University, Australia

2025 Organizing Committee, 16th International Conference on Ultrasound Engineering for Biomedical Applications (IC-UEBA 2025), Daegu, South Korea

2025 Session Chair, 16th International Conference on Ultrasound Engineering for Biomedical Applications (IC-UEBA 2025), Daegu, South Korea

2024 Plenary Speech Chair, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Conference Vice Chair, Global Conference on Biomedical Engineering (GCBME 2024), Tainan, Taiwan.

2024 Session Chair, 2024 IEEE UFFC-JS, Taipei, Taiwan

2023 Oral Presentation Judge, 2023 Annual Symposium of Taiwanese Society of Biomedical Engineering, Taiwan

2023 Session Chair, 2023 Annual Symposium of Taiwanese Societhy of Biomedical Engineering, Taiwan

2023 Advisory Committee, 2023 Annual Symposium of Taiwanese Society of Biomedical Engineering, Taiwan

2023 Technical Program Committee, 2023 Annual Symposium of Taiwanese Society of Biomedical Engineering, Taiwan

2023 Session Chair, 2023 IEEE International Ultrasonics Symposium, Montreal, Canada

2023 Project reviewer, PratikSha Trust Extra-Mural Support for Transformational Aging Brain Research (EMSTAR), India

2022 Session Chair, Global Conference on Biomedical Engineering (GCBME 2022), Taipei, Taiwan.

2022 Organizing Committee, Global Conference on Biomedical Engineering (GCBME 2022), Taipei, Taiwan.

2022 Project review committee, Dutch Research Council, Netherlands

2022 Session Chair, 2022 IEEE International Ultrasonics Symposium, Venice, Italy

2022 International Reviewers, Russian Science Foundation, Russian

2022 Expert Committee, Canada Foundation for Innovation’s 2023 Innovation Fund competition, Canada

2022 Project review committee, European Science Foundation

2022 Session Chair, 9th World Congress of Biomechanics, Taipei, Taiwan

2022 Session Chair, IUPESM World Congress on Medical Physics and Biomedical Engineering, Singapore

2022 Special Issue Editor, Piezoelectric Ultrasound Transducer for Biomedical Applications, Micromachines

2022 Reviewer, IFMBE Toh Siew Lok BME Student Design Award Competition, Singapore 

2021 Session Chair, 2021 IEEE International Ultrasonics Symposium, Xi’na, China

2020 International Technical Committee, Biomedical Engineering Conference BME2020: Fighting. COVID-19 and Future Pandemics with Innovation & Technology, Hong Kong

2020 Session Chair, 2020 IEEE International Ultrasonics Symposium, Las Vegas, USA

2020 Program Chair, IFMIA 2020 International Forum on Medical Imaging in Asia, Taiwan

2020 Social Program Chair, the 4th Global Conference of Biomedical Engineering & Annual Meeting of TSBME, Taipei, Taiwan

2020 Session Chair, the 11th Asian Pacific Conference on Medical and Biological Engineering, Okayama, Japan

2020 International Organizing Committee, the 11th Asian Pacific Conference on Medical and Biological Engineering, Okayama, Japan

2019 Session Chair, the 9th WACBE World Congress on Bioengineering, Taipei, Taiwan

2019 Social Program Chair, the 9th WACBE World Congress on Bioengineering, Taipei, Taiwan

2019 Session Chair, Future Trends in Biomedical and health Informatics & Cybersecurity in Medical. Devices conference, Taipei, Taiwan

2018 Poster Judge, 2018 Global Conference of Biomedical Engineering, Taoyuan, Taiwan

2018 Judge, Journal of Medical and Biological Engineering, Best Annual Paper Ward Competition, Taiwan

2018 Poster Session Chair, IEEE International Ultrasonics Symposium Proceedings, Kobe, Japan

2018 Judge for the Student Poster Competition, The 3rd Global Conference on Biomedical Engineering, Taiwan

2018 Chairman, Seminar on Southeast Asia Medical Device Regulation and Development, Taiwan

2017 Session Chair, International Congress of Ultrasound, Honolulu, USA

2017 Scientific Committee, the 16th World Federation for Ultrasound in Medicine and Biology. Congress, Taipei, Taiwan

2017 Session Chair, International Symposium of Frontier Acoustics, Shenzhen, China

2017 Session Chair, The Future Trend of Digital Health, Tainan, Taiwan

2017 Judge, 2017 Engineering Medical Innovation Global Competition, Taipei, Taiwan

2017 Session Chair, 2017 International Conference on Future Healthcare and Economic Development in Southeast ASIA, Taiwan

2017 Moderator, 2017 International conference on regulatory approaches for fostering innovation in drug and medical devices, Taiwan

2017 Supervisor, Teachers’ Association of National Cheng Kung University, Taiwan

2017 External Examiner of the Hong Kong Polytechnic University, Hong Kong.

2017 Session Chair, Fostering Innovation in Drugs and Medical Devices, Taiwan

2016 Session Chair, Focus and Enhance: Start of Interventional & Therapeutic Ultrasound, Taiwan

2016 Session Chair, Biomedical Engineering Ecosystem Symposium, Taiwan

2016 Committee of BME Innovation Competition, Taiwan

2016 Program Committee, International Forum on Medical Imaging in Asia, Japan

2016 Committee of Medical Device Registration, Taiwan Food and Drug Administration, Taiwan

2015 Committee of Ph.D Degree Defense, Hong Kong University, Hong Kong

2015 Session Chair, 12th Western Pacific Acoustic Conference, Singapore

2015 Audio-Visual Chair, IEEE International Ultrasonics Symposium, Taiwan

2015 Session Chair, 17th International Conference on Biomedical Engineering, Stockholm, Sweden

2015Session Co-Chair, IFMBE Young Investigator Competition, World Congress on Medical Physics& Biomedical Engineering, Toronto

2015 IFMBE Asia-Pacific Research Networking Fellowship, Taiwan-Japan-Canada

2015 Session Chair, Joint Conference of IWAIT&IFMIA, Taiwan

2015 Supervisor. Taiwanese Society of Biomedical Engineering

2015 Reviewer, Symposium on Engineering, Medicine and Biology Applications, Taiwan

2014 Lead Guest Editor, Journal of Electrical and Computer Engineering

2014 Session Chair, 2014 1st Global Conference on Biomedical Engineering (GCBME 2014) / 9th Asian-Pacific Conference on Medical and Biological Engineering, Taiwan.

2014 Reviewer, the 3rd International Conference on Biomedical Engineering and Biotechnology, China

2014 Reviewer, Biomedical Engineering Innovation Competition of Chung Yuan Christian University, Taiwan

2014 Committee of BME Innovation Competition, Taiwan

2014 Committee of the 2014 1st Global Conference on Biomedical Engineering (GCBME 2014) / 9th Asian-Pacific Conference on Medical and Biological Engineering, Taiwan.

2014 Reviewer, 2014 Symposium on Engineering Medicine and Biology Applications, Taiwan

2013 Session Chair, Taiwan-India Joint Symposium on Medical Device Innovation, Taiwan

2013 Committee of the 5th Asian Conference on Ultrasound Contrast Imaging, Taiwan

2013 Committee of the 2013 International Conference on Biomedical Ultrasound, Taiwan

2013 Session Chair, Symposium of Annual Conference of the Biomedical Engineering Society, Taiwan

2013~2015: Vice Secretary General, Taiwanese Society of Biomedical Engineering

2012~2015: Editor, Taiwanese Society of Biomedical Engineering E-Newsletter

2013 Reviewer, 2013 Symposium of Annual Conference of the Biomedical Engineering Society, Taiwan

2013 Reviewer, IEEE Biomedical Circuits & Systems Conference, Netherlands

2013 Session Chair, Symposium on Engineering Medicine and Biology Applications, Taiwan

2012 Session Chair, Symposium of Annual Conference of the Biomedical Engineering Society, Taiwan

2012 Reviewer, 2012 Symposium of Annual Conference of the Biomedical Engineering Society, Taiwan

2011 Session Chair, 5th WACBE World Congress on Bioengineering, Taiwan

2011 Committee of Poster Paper Competition, Symposium of Annual Conference of the Biomedical Engineering Society, Taiwan

2010 Session Chair, Symposium of Annual Conference of the Biomedical Engineering Society, Taiwan

2010 Reviewer, National Symposium on Telecommunications, Taiwan

2009 Reviewer, National Symposium on Telecommunications, Taiwan

2008 Reviewer, Symposium of Annual Conference of the Biomedical Engineering Society, Taiwan

2008 Committee of Poster Paper Competition, Symposium of Annual Conference of the Biomedical


Educational Background

2003~2007: Ph.D., Biomedical Engineering, Chung Yuan Christian University, Taiwan

2002~2003: M.S., Biomedical Engineering, Chung Yuan Christian University, Taiwan

1998~2002: B.S., Biomedical Engineering, Chung Yuan Christian University, Taiwan


Job Description

To study the basic knowledge of medical devices.

Preferred Intern Educational Level

From undergraduate to doctoral student.

Skill sets or Qualities

computer coding.