Fu Jen Catholic University

Laboratory of Chemical Microchip and Biomedical Mass Spectrometry

Hui-Ling Lee
https://sites.google.com/view/ch312

Research Field

Chemistry
Introduction

Principal Investigator, Group Leader

I am a well-trained analytical chemist with a research background in various areas of research. My expertise includes the development of analytical methods, design and synthesis of MOFs and COFs and the use of LC-MS/MS, GC-MS and electrochemical sensor techniques to investigate interactions between novel materials and environmental pollutants. Currently, our research projects develop of novel materials for sample pretreatment design, where we utilize simple synthesis to create innovative novel materials and explore the properties for functional applications.

 

 

  • Application of HPLC-MS/MS for the analysis of environmental pollutants (e.g., arsenic, second-hand smoke, nanomaterials, VOCs, PM2.5, PAHs) and their health-related biomarkers, such as 8-OHdG (oxidative DNA damage), global DNA methylation, 8-iso-prostaglandin F2α (lipid peroxidation), metabolites of cigarette carcinogen NNK, and VOC metabolites.
  • Use of LC-Q-TOF mass spectrometry for exposomics studies in animal models and human exposure, conducting comprehensive metabolite profiling and targeted analysis to identify novel biomarkers such as amino acids, tryptophan metabolites, arachidonic acid metabolites, and perfluoroalkyl substances (PFAS).
  • Development of novel materials for sample pretreatment, including metal–organic frameworks (MOFs), covalent–organic frameworks (COFs), and magnetic nanomaterials.

Graduate Student

We invite talented college graduates with backgrounds in organic chemistry, physical chemistry, and analytical chemistry to join our team at FJCU and pursue their academic goals as PhD students.  You can find detailed information on the FJCU graduate program website or reach out to us via email for further inquiries.

Visiting graduate student

Joint graduate students are also welcome to work in our group at FJUCU. Students who are interested in this program can send an email to us to discuss education plans in detail.

Research Topics
  • Application of HPLC-MS/MS for the analysis of environmental pollutants (e.g., arsenic, second-hand smoke, nanomaterials, VOCs, PM2.5, PAHs) and their health-related biomarkers, such as 8-OHdG (oxidative DNA damage), global DNA methylation, 8-iso-prostaglandin F2α (lipid peroxidation), metabolites of cigarette carcinogen NNK, and VOC metabolites.
  • Use of LC-Q-TOF mass spectrometry for exposomics studies in animal models and human exposure, conducting comprehensive metabolite profiling and targeted analysis to identify novel biomarkers such as amino acids, tryptophan metabolites, arachidonic acid metabolites, and perfluoroalkyl substances (PFAS).
  • Development of novel materials for sample pretreatment, including metal–organic frameworks (MOFs), covalent–organic frameworks (COFs), and magnetic nanomaterials.

We very welcome young talented students who are interested in the development of functional materials in the analytical biological area to pursue their academic goals in our team at FJCU.

Honor
  1. Outstanding Research Award (Academic Year 2013) – Awarded on April 12, 2015
  2. Class Advisor Excellence Award – Awarded on November 11, 2015
  3. Teaching Achievement Award – Awarded on January 7, 2016
  4. Outstanding Talent Award by the Ministry of Science and Technology – 2014
  5. Outstanding Talent Award by the Ministry of Science and Technology – 2015
  6. Outstanding Talent Award by the Ministry of Science and Technology – 2016
  7. Outstanding Talent Award by the Ministry of Science and Technology – 2017
  8. Outstanding Talent Award by the Ministry of Science and Technology – 2018
  9. Outstanding Talent Award by the Ministry of Science and Technology – 2019
  10. Outstanding Talent Award by the Ministry of Science and Technology – 2020
  11. Outstanding Talent Award by the Ministry of Science and Technology – 2021
  12. Outstanding Talent Award by the Ministry of Science and Technology – 2022
  13. Outstanding Talent Award by the Ministry of Science and Technology – 2023
  14. Outstanding Talent Award by the Ministry of Science and Technology – 2024
  15. Outstanding Research Award (Academic Year 2018) – Awarded on February 11, 2020
  16. Chao-Chao Distinguished Chair Professorship (Three Academic Years: Feb. 1, 2021 – Jan. 31, 2024)
Educational Background

Work and Research Experience

  • Postdoctoral Research Fellow, Division of Environmental Health and Occupational Medicine, National Health Research Institutes (2008)
  • Assistant Professor, Department of Chemistry, Fu Jen Catholic University (Feb. 2009-Aug. 2012)
  • Associate Professor, Department of Chemistry, Fu Jen Catholic University (Feb. 2012-July. 2017)
  • Professor, Department of Chemistry, Fu Jen Catholic University (Aug. 2017 – Jan. 2025)
  • Distinguished Professor, Department of Chemistry, Fu Jen Catholic University (Jan. 2025 – Present)
  • Director, Environmental Safety and Health Center, Fu Jen Catholic University (Aug. 2018 – Jul. 2020)
  • Chair, Department of Chemistry, Fu Jen Catholic University (Aug. 2020 – Jul. 2023)

Education

  • B.S., Department of Chemistry, Kaohsiung Medical University (1995)
  • Ph.D., Analytical Chemistry, Graduate Institute of Chemistry, Fu Jen Catholic University (2004)