Job Description

We are looking for motivated and talented individuals to join our research team to contribute to the development of magnetic bead sensing technology for the precise screening and isolation of extracellular vesicles (EVs) with specific exosomal CD markers (e.g., CD63, CD9, CD81). This internship or research opportunity offers hands-on experience in advanced biomedical research, focusing on innovative techniques for extracellular vesicle isolation and analysis.
As part of the team, you will work on optimizing and applying a novel microfluidic-based magnetic bead sensing platform. This technology integrates antibody specificity with magnetic capture techniques to efficiently isolate and purify extracellular vesicles with targeted exosomal markers. Responsibilities include:
•    System Development and Optimization: Assist in the design and operation of a microfluidic-based magnetic bead sensing system to collect and isolate EVs. Contribute to enhancing the binding efficiency between EVs and magnetic beads using optimized flow channel designs and antibody-coated surfaces.
•    Experimental Implementation: Perform experiments to isolate EVs using magnetic beads coated with antibodies against specific exosomal markers (CD63, CD9, CD81). Analyze the efficiency of binding, separation, and recovery rates under controlled conditions.
•    EV Characterization: Assist in characterizing isolated EVs using imaging and biochemical methods. Evaluate their biochemical composition and purity for downstream applications.
•    Protocol Development: Help refine the step-by-step protocol for magnetic bead isolation, including the capture and release of target EVs using MgCl₂ solutions to break antigen-antibody bonds.
•    Innovation Exploration: Contribute to the design of an automated microfluidic chip for precise EV screening and isolation. Test and validate the system for scalability and reproducibility in various experimental conditions.
•    Documentation and Reporting: Maintain detailed experimental records and prepare data reports to support project findings. Contribute to scientific presentations and publications.
This opportunity is ideal for students or researchers with backgrounds in biomedical engineering, biotechnology, or related fields. Prior experience or interest in microfluidics, antibody-based techniques, and extracellular vesicle research is highly encouraged. Strong analytical skills, attention to detail, and a willingness to collaborate in a multidisciplinary team are essential.

Preferred Intern Educational Level

We welcome applications from undergraduate students in their third year or above, as well as graduate students. This opportunity is ideal for those with a background or strong interest in biomedical engineering, biotechnology, molecular biology, or related fields.

Skill sets or Qualities

1.    Technical Knowledge:
    Has an interest in or is familiar with basic laboratory techniques in molecular biology, biophotonics, or biotechnology.
    Demonstrates curiosity or prior experience with antibody-based binding techniques, particularly in extracellular vesicle research.
    Enthusiastic about or has a basic understanding of optical systems such as Raman spectroscopy or microfluidics.
2.    Analytical Skills:
    Interested in developing skills for analyzing and interpreting experimental data with precision and attention to detail.
    Familiarity with data analysis tools (e.g., ImageJ, Excel) or a willingness to learn and use them effectively.
3.    Problem-Solving:
    Has a proactive approach to troubleshooting experimental setups and optimizing protocols.
4.    Collaboration:
    Strong communication skills and a willingness to collaborate effectively in a multidisciplinary research team.
    Open to sharing ideas and learning from others.
5.    Organizational Skills:
    Able to maintain detailed and accurate experimental records.
    Capable of managing time effectively to meet project milestones and deadlines.
6.    Adaptability and Enthusiasm:
    Eager to learn and adapt to new techniques and technologies in a dynamic research environment.
    Displays genuine interest in advancing research on extracellular vesicle isolation and biomedical innovation.
7.    Language Proficiency:
    Comfortable communicating in English for scientific discussions, documentation, and reporting.
 

Job Description

We are looking for motivated and talented individuals to join our research team to contribute to the development of magnetic bead sensing technology for the precise screening and isolation of extracellular vesicles (EVs) with specific exosomal CD markers (e.g., CD63, CD9, CD81). This internship or research opportunity offers hands-on experience in advanced biomedical research, focusing on innovative techniques for extracellular vesicle isolation and analysis.
As part of the team, you will work on optimizing and applying a novel microfluidic-based magnetic bead sensing platform. This technology integrates antibody specificity with magnetic capture techniques to efficiently isolate and purify extracellular vesicles with targeted exosomal markers. Responsibilities include:
•    System Development and Optimization: Assist in the design and operation of a microfluidic-based magnetic bead sensing system to collect and isolate EVs. Contribute to enhancing the binding efficiency between EVs and magnetic beads using optimized flow channel designs and antibody-coated surfaces.
•    Experimental Implementation: Perform experiments to isolate EVs using magnetic beads coated with antibodies against specific exosomal markers (CD63, CD9, CD81). Analyze the efficiency of binding, separation, and recovery rates under controlled conditions.
•    EV Characterization: Assist in characterizing isolated EVs using imaging and biochemical methods. Evaluate their biochemical composition and purity for downstream applications.
•    Protocol Development: Help refine the step-by-step protocol for magnetic bead isolation, including the capture and release of target EVs using MgCl₂ solutions to break antigen-antibody bonds.
•    Innovation Exploration: Contribute to the design of an automated microfluidic chip for precise EV screening and isolation. Test and validate the system for scalability and reproducibility in various experimental conditions.
•    Documentation and Reporting: Maintain detailed experimental records and prepare data reports to support project findings. Contribute to scientific presentations and publications.
This opportunity is ideal for students or researchers with backgrounds in biomedical engineering, biotechnology, or related fields. Prior experience or interest in microfluidics, antibody-based techniques, and extracellular vesicle research is highly encouraged. Strong analytical skills, attention to detail, and a willingness to collaborate in a multidisciplinary team are essential.
 

Preferred Intern Educational Level

We welcome applications from undergraduate students in their third year or above, as well as graduate students. This opportunity is ideal for those with a background or strong interest in biomedical engineering, biotechnology, molecular biology, or related fields.

Skill sets or Qualities

1.    Technical Knowledge:
    Has an interest in or is familiar with basic laboratory techniques in molecular biology, biophotonics, or biotechnology.
    Demonstrates curiosity or prior experience with antibody-based binding techniques, particularly in extracellular vesicle research.
    Enthusiastic about or has a basic understanding of optical systems such as Raman spectroscopy or microfluidics.
2.    Analytical Skills:
    Interested in developing skills for analyzing and interpreting experimental data with precision and attention to detail.
    Familiarity with data analysis tools (e.g., ImageJ, Excel) or a willingness to learn and use them effectively.
3.    Problem-Solving:
    Has a proactive approach to troubleshooting experimental setups and optimizing protocols.
4.    Collaboration:
    Strong communication skills and a willingness to collaborate effectively in a multidisciplinary research team.
    Open to sharing ideas and learning from others.
5.    Organizational Skills:
    Able to maintain detailed and accurate experimental records.
    Capable of managing time effectively to meet project milestones and deadlines.
6.    Adaptability and Enthusiasm:
    Eager to learn and adapt to new techniques and technologies in a dynamic research environment.
    Displays genuine interest in advancing research on extracellular vesicle isolation and biomedical innovation.
7.    Language Proficiency:
    Comfortable communicating in English for scientific discussions, documentation, and reporting.