Ching-Ching Yu laboratory
Research Field
2022 ~ Associate Professor of NTHU 2021 ~ Joint Appointment Associate Research Fellow, Institute of Biological Chemistry, Academia Sinica 2020 ~ 2022 AssociateProfessor of NCCU 2015 ~ 2020 Assistant Professor of NCCU 2014 ~ 2015 Postdoc Research Fellow, Dept. of Chemistry University of British Columbia, BC, Canada 2013 ~ 2014 Postdoc Research Fellow, Dept. of Chemistry NTHU
Our research program is focused in the areas of biosynthetic chemistry (with a particular emphasis in enzymatic carbohydrate synthesis), the structure determination/analysis of oligosaccharides and the discovery of novel carbohydrate-active enzymes that can be used in complex oligosaccharide synthesis. Students and postdoctoral fellows in the group use synthetic chemistry and enzymatic strategy to prepare compounds with interesting biological activities and then have the opportunity to use them in either biochemical or conformational studies.
The long-term goals of our research program are to develop state-of-the-art methods for assembling complex, biologically-relevant carbohydrates (glycans) that can be used to probe their function in nature. My underlying research philosophy is to work on problems in which developing methods for preparing novel, structurally-interesting glycans leads to tools for studying vital biological problems. The major area of focus is human milk glycans. Specific systems of interest are: 1) Discovering new enzymes as biocatalysts for human milk-type glycan synthesis; 2) Chemoenzymatic synthesis of the human milk oligosaccharide library; and 3) The function of human milk oligosaccharides in human gut microbiota and to investigate their roles in preventing the pathogenic infections.
Carbohydrate Chemistry, Carbohydrate Biochemistry, Glycobiology, Enzyme Chemistry
| 2022 | The Chinese Chemical Society "Young Chemists Award" |
| 2022 | XXIII Shu-Mu Foundation of Chemistry "Young Chemist Award" |
| 2021 | Taiwan Comprehensive University System (TCUS) "Excellent Award in the associate professor and assistant professor group of the Young Scholar Innovative Research Competition" |
| 2021 | Ministry of Science and Technology "Project for Excellent Junior Research Investigators" |
| 2021 | Ministry of Science and Technology "Ta-You Wu Memorial Award" |
| 2021 | Young Scholar Award at National Chung Cheng University |
| 2021 | Dept. Chem. & Biochem., National Chung Cheng University "Excellent Teaching Award" |
| 2019 | Dept. Chem. & Biochem., National Chung Cheng University "Excellent Teaching Award" |
PhD, National Tsing Hua University (2012)
MS, National Chung Hsing University (2007)
BS, National Chang Hua University of Education (2007)
Job Description
This position is intended for students with a strong interest in synthetic chemistry and interdisciplinary research at the interface of organic chemistry, biochemistry, and molecular biology. Because these internships are expected to support potential long-term academic exchange and collaboration, applicants are strongly encouraged to apply through prior contact between their academic advisor and our laboratory.
Preferred Intern Educational Level
Applicants should preferably hold a master’s degree or currently be enrolled in a master’s or Ph.D. program in chemistry, biochemistry, molecular biology, or a closely related field.
Skill sets or Qualities
Candidates should have a solid foundation in organic synthesis. Prior knowledge of biochemistry or molecular biology is also desirable. We welcome applicants who are careful in experimental work, motivated to learn, and able to work independently as well as collaboratively in a research environment. Preference will be given to students whose advisors have established prior contact with our group and where there is potential for future collaboration.
Job Description
This position is intended for students with a strong interest in synthetic chemistry and interdisciplinary research at the interface of organic chemistry, biochemistry, and molecular biology. Because these internships are expected to support potential long-term academic exchange and collaboration, applicants are strongly encouraged to apply through prior contact between their academic advisor and our laboratory.
Preferred Intern Educational Level
Applicants should preferably hold a master’s degree or currently be enrolled in a master’s or Ph.D. program in chemistry, biochemistry, molecular biology, or a closely related field.
Skill sets or Qualities
Candidates should have a solid foundation in organic synthesis. Prior knowledge of biochemistry or molecular biology is also desirable. We welcome applicants who are careful in experimental work, motivated to learn, and able to work independently as well as collaboratively in a research environment. Preference will be given to students whose advisors have established prior contact with our group and where there is potential for future collaboration.