Kaohsiung Medical University

Microfluidic Laboratory

Wei-Yu Lin
wp.kmu.edu.tw/wylin

Research Field

Chemistry

Introduction

https://wp.kmu.edu.tw/wylin/

Professor Wei-Yu Lin's research interests focus on the (i) Development of a new methodology for organic synthesis using a continuous flow system as a platform. The general concept is based on high-resolution time control using flow microreactors to enable chemical reactions that cannot be done in a batch condition. (ii) Metal-Catalyzed cyclization for the construction of heterocyclic derivatives, including the indoles, quinolines, quinazolinone and indazolone (iii) Selective for the C-N Bond activation by a simple method (iv) Biorthogonal approach for the in vivo imaging using a pretargeted oncologic positron emission tomography (PET) imaging that leverages the power of supramolecular nanoparticles with in vivo bioorthogonal chemistry was demonstrated to the clinically relevant problem of tumor imaging. The research result is summarized below:


Research Topics

https://wp.kmu.edu.tw/wylin/%e7%a0%94%e7%a9%b6%e8%88%88%e8%b6%a3/


Honor

2024         Asian Core Program Lectureship Award, Korea.

2023         Everlight Chemical Green Chemistry Award, Chinese Chemical Society/Taipei/Taiwan

2023         Asian Core Program Lectureship Award, Japan.

2016-2021     Outstanding Research Award, Kaohsiung Medical University


Educational Background

學歷(Education):

成功大學化學系學士(1998) B. S. in Chemistry, National Cheng-Kung University.

台灣大學化學系碩士(2001) M. S. in Organic Chemistry, National Taiwan University

台灣大學化學系博士(2006) Ph. D. in Organic Chemistry, National Taiwan University


 


Job Description

Study and learn advanced organic continuous-flow synthesis, as well as state-of-the-art synthetic technologies, such as ultrasonic and ball-milling reactions.

https://wp.kmu.edu.tw/wylin/8-2/

Preferred Intern Educational Level

Applicants must hold a master’s degree and have a major in organic chemistry with a background in synthetic chemistry.

Skill sets or Qualities

Applicants must hold a master’s degree and have a major in organic chemistry with a background in synthetic chemistry.

Job Description

Sulfur's pivotal role in biologically active molecules has driven significant interest in developing mild synthetic methodologies. However, efficient approaches for C-S and C-N bond formation remain challenging. We will study the activation of gem-dihaloacetate by elemental sulfur to produce asymmetric monothiooxalamides, which serve as active ligands in copper-catalyzed C-N cross-coupling reactions. Additionally, we wish to report the synthesis of α-ketothioamide through C-S/C-N bond formation via epoxide ring opening, enhancing reaction efficiency. 

https://wp.kmu.edu.tw/wylin/8-2/

Preferred Intern Educational Level

Applicants must possess a master’s degree in organic chemistry, with demonstrated training or experience in synthetic chemistry.

Skill sets or Qualities

Applicants must possess a master’s degree in organic chemistry, with demonstrated training or experience in synthetic chemistry.