The mentor has been actively engaged in immunology research while serving as an associate professor at National Tsing-Hua university. He possesses extensive knowledge and research experience in the field of immunology, with a particular expertise in the regulation of T-cell responses. Throughout his career, he has been focusing on studying the mechanisms and therapeutic approaches related to immune checkpoint molecules (CD28, CTLA-4, PD-1) .
Our lab focuses on T lymphocyte activation and tolerance. We work on fundamental mechanisms determining if T cells react or do not react with pathogen, self tissue and cancer. Also we seek novel methods to systemically control T cell tolerance, which ultimately leads to control of numerous diseases and healthy aging.
1.T lymphocyte activation and tolerance
We work on fundamental mechanisms determining if T cells react or do not react with pathogen, self tissue and cancer.
2. Novel Methods to Target T cells in Autoimmunity, Cancer and Aging
We seek novel methods to systemically control T cell tolerance, which ultimately leads to control of numerous diseases and healthy aging.
1st Kishimoto Award. April 2011
Given to Research on “Type I interferon promotes PD-1 transcription and limits the duration of T cell-mediated immunity.”
March, 1997
Graduated, School of Veterinary Medicine, Hokkaido University, Sapporo, JAPAN (Doctor of Veterinary Medicine)
March, 2001
Ph. D. Medicine, Graduate school of Medicine, Hokkaido University, Sapporo, JAPAN