Lane Lab
Research Field
Lucas Lane is an Assistant Professor at Taipei Medical University (TMU), specializing in Biomedical Engineering, particularly in nanobiosensing and stimuli-responsive nanocarriers, and holds a Ph.D. from Georgia Tech. He is a member of TMU's International Ph.D. Program in Biomedical Engineering and Graduate Institutes of Biomedical Optomechatronics.
My research focuses on the development and clinical translation of optical-based biomedical technologies. Current projects in my laboratory include using surface-enhanced Raman scattering (SERS) and fluorescence techniques for image-guided surgery, quantitative diagnostics, and the study of cancer pathophysiology. Above all, I aim to make scientific contributions that increase survival rates and improve the quality of life for patients struggling with complex diseases.
- Using SERS nanotags as probes to investigate optimal parameters in nanomedicine design
- Using SERS nanotags to detect rare cancer cells in complex biological solutions
- Using biomimetic coatings to increase the delivery and uptake of nanomedicines and optical imaging probes
Distinguished Professorship, "Lifenergy Scholar", Nanjing University 2017
Selected as part of the 13th batch in China's National 1000 Global Talents Project 2017
Best Poster Presentation, Institute for Electronics and Nanotechnology at Georgia Tech 2013
2nd Place Student Paper Competition, American Institute of Chemical Engineers 2009
Georgia Institute of Technology, Ph.D. in Bioengineering, 2014
Dissertation title: Advancement of Blinking Suppressed Quantum Dots for Enhanced Single Molecule Imaging
Minor: Nonlinear and Applied Mathematics
Thesis Committee: Shuming Nie (Advisor). Younan Xia, Mostafa El-Sayed, Gang Bao, Adam Marcus
Washington University in St. Louis, B.S. in Applied Science, 2009
Job Description
The intern will synthesize gold nanoparticles of different shapes and sizes. Culture various cells and extract their membranes for use as nanoparticle coatings. Apply the optical probes to various cell cultures to analyze specific binding and uptake over time. Use in vivo tumor models to determine which constructs have optimal circulation and tumor-targeting characteristics. Use SERS techniques to analyze multiple particle constructions in a single setting.
Preferred Intern Educational Level
Preference is for students to have a background in the physical and chemical sciences, along with some previous experience in chemical synthesis techniques, optical imaging, and dealing with cells or animal models.
Skill sets or Qualities
Familiar with the synthesis of inorganic nanoparticles
Cell culture
Familiar with basic optical principles
Job Description
Using the software package COMSOL to calculate electric field enhancements and the extinction, scattering, and absorption properties of various particle configurations.
Preferred Intern Educational Level
Undergraduate with experience in calculus and differential equations. Preferred experience with computational techniques and classes that solve partial differential equations analytically, along with classes in optics, electromagnetics, or both.
Skill sets or Qualities
Mathematical ability at the level of differential equations
Familiarity with Finite element methods
Familiarity or had courses in electromagnetics and optics