Introduction

Michal Kořínek is a Pharmacist (Ms..) who graduated from Charles University in Prague, Faculty of Pharmacy, Czech Republic. He participated in the European cooperative research program ERASMUS at Eastern University in Finland (PharmDr.) and the student exchange program organized by IPSF in Taiwan (community pharmacy). He obtained Ph.D. degree at the Graduate Institute of Natural Products, Kaohsiung Medical University. The research directions include bioactivity-guided extraction, separation, and isolation of immune-modulating components using bioinformatic tools (molecular docking and networking), with the aim of discovering new drugs from natural sources. Additionally, we validate the traditional efficacy of herbs, providing scientific clarity on their properties from both phytochemical and pharmacological perspectives.

Our laboratory is dedicated to the 'Discovery of active natural products' through the systematic extraction and isolation of bioactive molecules. Our research program focuses on:

  • Natural Product Chemistry: Advancing methodologies for the extraction, separation, and purification of specialized metabolites.
  • Mechanistic Validation: Providing a phytochemical basis for the traditional use of herbal medicines in treating immune-related diseases, supported by collaborative biological assays.
  • Resource Valorization: Biodiversity prospecting of edible plants and agricultural byproducts (waste) to identify novel leads for pharmaceutical development.
     


Research Topics

1.    Plant material extraction, bioactive fraction separation, and pure compound isolation using various chromatographic techniques (TLC, column chromatography, MPLC, HPLC).

2.    Pure compounds structural elucidation (NMR, MS).

3.    Utilizing bioinformatic tools (molecular docking and networking) to aid the discovery of new drugs.

We prefer that student works in the wet lab which may enhance the results of current students’ project-related topics or initiate new topics in the field or cross-field. 


Honor

Awarded 4 NSTC, 2 KMU, and 1 NSYSU-KMU projects.

Member of The Society of Chinese Natural Medicine (Taiwan), since 2020
Member of Society for Medicinal Plant and Natural Product Research (GA; official European Pharmacognosy Society), since 2023

2021 Outstanding Research Award, KMU 年度研究績優教師 

Review Editor, Frontiers in Pharmacology, since 2020

Invited Speaker and Best Poster award at several international conferences

Thesis Excellence Competition Award, Faculty of Pharmacy, Charles University


Educational Background

M.S. (Mgr.) degree at Charles University in Prague, Czech Republic 🇨🇿, 2003/09 - 2008/06 (field Pharmacy)

Pharm.Dr. (Czech Republic) degree at University of Eastern Finland, Finland 🇫🇮 & Charles University, Czech Republic 🇨🇿, 2009/03 - 2009/09 (field Medicinal Chemistry)

Ph.D. degree at Kaohsiung Medical University, Taiwan 🇹🇼,   2009/10 - 2017/06 (field Pharmacognosy)